For Professionals
What is nano-Hydroxyapatite?
Hydroxyapatite is the major component of dental hard tissue, corresponding to 97% of the enamel and up to 68% of dentin. The tooth enamel building blocks are hydroxyapatite crystals that can hardly be repaired naturally at a rate that maintains teeth integrity avoiding hypersensitivity.
Nano-Hydroxyapatite (nHAp™) helps to avoid the development of white spot lesions due to it’s strong remineralizing efficacy. nHAp™ should be used frequently to ensure that the nano hydroxyapatite particles can penetrate and adhere into cracks, calcium deficiencies and open tubules.
White Spot Lesions
White spot lesions occur due to the de-mineralization, loss of important minerals from the enamel. Areas around the braces are especially vulnerable to this de-mineralization. OrthoCare™ products are specially designed to protect and repair the enamel with a biocompatable nano-hydroxyapatite (nHAp™), which is the same mineral that makes up a majority of the teeth.
The use of OrthoCare™ during the entire orthodontic procedure significantly helps prevent the development of these white spot lesions.
Advantages of using OrthoCare™ Fluoride Free, nHAp™ based oral care products
Prevents the development of white spot lesions.
Biocompatable enamel repair and protection.
Eliminates tooth hypersensitivity.
Makes teeth whiter and glossier.
Easy to use, just replace current toothpaste with OrthoCare™ products.
Before nHAp™ treatment
After nHAp™ treatment
Research
Remineralization & Repair
Annali di Stomatologia 2014; V (3): 108-114
Scientific Research and Essays Vol. 6(26), pp. 5933-5936, 16 November, 2011
Remineralization of Early Caries by a Nano-Hydroxyapatite Dentifrice
The Journal of Clinical Dentistry vol. 22 (2011) nr. 5
Research about bovine teeth brightness with using dentifrice slurry including nano-hydroxyapatite
Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference, 16-18 October 2010, vol. 5
Beneficial effects of hydroxyapatite on enamel subjected to 30% hydrogen peroxide
Journal of dentistry 36 (2008) 907 – 914
Repair of enamel by using hydroxyapatite nanoparticles as the building blocks
www.rsc.org/materials | Journal of Materials Chemistry, 18th July 2008
In Situ Remineralization of Early Caries Lesions by Nano-hydroxyapatite Dentifrice
88th General Session & Exhibition of the IADR, July 14-17, 2010
Tschoppe P, et al. Enamel and dentine remineralization by nano-hydroxyapatite toothpastes
Journal of Dentistry(2011), doi:10.1016/j.jdent.2011.03.008
A New Enamel Restoring Agent for Use after Bleaching
H. Kawamata, 2004
Sensitivity Management
Hindawi Publishing Corporation, International Journal of Dentistry Volume 2013, Article ID 573258
RRJDS, Volume 2, Issue 2, April - June, 2014
Occlusion of Dentinal Tubules by Nano-Hydroxyapatite
Journal of Dental Research, Vol.86, Special Issue A(New Orleans Abstracts), 2007
Oral Hyg Health 1: 104. doi:10.4172/johh.1000104
nHAp™ Biocompatibility
C. Albrecht et al. / Toxicology in Vitro 23 (2009) 520–530
Toxicity of hydroxyapatite nanoparticles on rabbits
Wei Sheng Yan Jiu. 2005 Jul;34(4):474-6. PubMed - NCBI
J. Scheel et al. / Toxicology in Vitro 23 (2009) 531–538
Indian Journal of Medical Specialities, Vol. 3, No. 2, Jul - Dec 2012
nHAp™ Anti- Bacteria
Adsorption Effect of Hydroxyapatite to Oral Streptococci
Journal of Dental Research, Vol.81, Special Issue A(San Diego Abstracts), A-200, 2002
Interaction of Small Crystal Form of Hydroxyapatite with Mutans Steptococci
Journal of Dental Research, Vol.82, Special Issue B(Goteborg Abstracts), B-81, 2003
Reduction of Oral Mutans Streptococci by Small-Crystal Hydroxyapatite
Journal of Dental Research, Vol.83, Special Issue A(Honolulu Abstracts), 2004
Unique Functions of Hydroxyapatite with Mutans Streptococci Adherence
Quintessence International, 41(1),e11-19,2010
Adsorption of oral pathogenic microbes by small crystal hydroxyapatite
Journal of Dental Research, Vol.86, Special Issue A(New Orleans Abstracts), 2007
Evaluation of Cariogenic Bacteria Removal by Nano-hydroxyapatite
88th General Session & Exhibition of the IADR, July 14-17, 2010
Key Engineering Materials Vols. 330-332 (2007) pp 283-286
Reduction in Oral MS Ratios by Nano-Hydroxyapatite: a Clinical Trial
Friday, March 22, 2013: 10:45 a.m. - 12:15 p.m. (Washington State Convention Center), Oral Session
Antibacterial property of locally produced hydroxyapatite
Tin-Oo et al. Archives of Orofacial Sciences (2007) 2, 41-44
Calcium Modulates Interactions between Bacteria and Hydroxyapatite
JDR December 2006 vol. 85 no. 12 1124-1128
nHAp™ vs Fluoride
Hindawi Publishing Corporation, The Scientific World Journal, Volume 2014, Article ID 293019
Recent Patents on Biomedical Engineering 2009, 2, 197-215
Oral Hyg Health 1: 104.doi:10.4172/johh.1000104
Enamel surface remineralisation: Using synthetic nano-hydroxyapatite
Contemporary Clinical Dentistry, Oct-Dec 2012. Vol 3, Issue 4
Enamel and dentine remineralization by nano-hydroxyapatite toothpastes
Journal of dentistry 39(2011)430 – 437
Whitening & Smoothening
Restoration of Post-Bleach Enamel Gloss Using a Non-Abrasive, Nano-Hydroxyapatite Conditioner
84th General Session & Exhibition of the IADR, June 28-July 1, 2006
Effects of Fluoride or Nanohydroxiapatite on Roughness and Gloss of Bleached Teeth
A.C.P. De Freitas et al. Microscopy Research and Technique 00:000–000 (2011)
Polishing and whitening properties of toothpaste containing hydroxyapatite
Journal of Materials Science: Materials in Medicine 12 (2001) 277-281
Overall Benefits
Nanomaterials in preventive dentistry
Nature Nanotechnology doi: 10.1038/nnano.2010.83`
The Biomimetic Approach to Design Apatites for Nano-biotechnological Applications
Roveri et. al. (2010)